Skip to main content

Table 2 Seed sequences enriched in high scoring siRNAs

From: Systematic analysis of off-target effects in an RNAi screen reveals microRNAs affecting sensitivity to TRAIL-induced apoptosis

Seed Size Normalized Enrichment Score FWER p-val
Hexamers    
TAATAA 70 2.691 0
ACTTGA 14 2.674 0
CCTTAA 16 2.642 0
AATTAA 44 2.567 0
ACTGGA 10 2.510 0
TAGGAA 13 2.505 0
TAAAGA 20 2.482 0.002
GAATAA 21 2.474 0.002
AAGTTA 20 2.426 0.004
TCACAA 12 2.413 0.005
AAATGA 21 2.405 0.005
AGATCA 35 2.378 0.006
TTATAA 22 2.335 0.009
AATATT 15 2.314 0.015
AGATCT 17 2.304 0.015
TGAATA 16 2.255 0.026
CTGGAA 8 2.198 0.047
Heptamers    
CAATTAA 18 2.911 0.000
GAGATCA 18 2.387 0.001
GAAAGAA 10 2.241 0.015
TTAATAA 17 2.227 0.015
GTATTTA 16 2.211 0.016
ATAGGAA 6 2.187 0.021
ACCTTAA 8 2.185 0.021
TAATTAA 8 2.179 0.024
TTAATTA 10 2.151 0.037
ACAATTA 10 2.148 0.039
AAGATCA 13 2.140 0.041
CTAATAA 20 2.139 0.041
CTAATTA 7 2.136 0.043
  1. Table shows seed sequences designated enriched in high scoring siRNAs by GSEA. The number the seeds in the set, the enrichment score and the multiple testing corrected P value are shown.