Table 1 Results of gene ontology analysis using the "biological process" annotation
GO category | # genes | ER | NC | p-value |
|---|---|---|---|---|
(A) | Â | Â | Â | Â |
humoral defense mechanism sensu Vertebrata | 11 | 1.58 | 4.3 | 0 |
antigen presentation | 11 | 1.54 | 4.02 | 0 |
defense response | 46 | 1.34 | 2.72 | 0 |
immune response | 102 | 1.28 | 2.31 | 0 |
positive regulation of transcription | Â | Â | Â | Â |
DNA-dependent | 13 | 1.19 | 1.65 | 0.0013 |
regulation of apoptosis | 45 | 1.11 | 0.94 | 0.0005 |
protein ubiquitination | 78 | 1.06 | 0.58 | 0.0049 |
protein modification | 71 | 1.06 | 0.57 | 0 |
transcription | 449 | 1.04 | 0.34 | 0 |
regulation of transcription DNA.dependent | 586 | 1.03 | 0.29 | 0 |
transport | 576 | 0.97 | -0.29 | 0.0002 |
electron transport | 138 | 0.95 | -0.49 | 0.002 |
metabolism | 151 | 0.92 | -0.8 | 0 |
sodium ion transport | 22 | 0.88 | -1.2 | 0.0025 |
biosynthesis | 24 | 0.87 | -1.26 | 0.0009 |
fatty acid biosynthesis | 15 | 0.85 | -1.57 | 0.0011 |
lipid biosynthesis | 34 | 0.83 | -1.77 | 0 |
steroid biosynthesis | 20 | 0.83 | -1.79 | 0 |
cholesterol biosynthesis | 12 | 0.79 | -2.21 | 0 |
sterol biosynthesis | 13 | 0.77 | -2.5 | 0 |
(B) | Â | Â | Â | Â |
inflammatory response | 46 | 2.24 | 7.55 | 0 |
chemotaxis | 30 | 2 | 6.48 | 0 |
immune response | 102 | 1.93 | 6.18 | 0 |
sensory perception | 42 | 1.64 | 4.66 | 0 |
defense response to bacteria | 11 | 1.63 | 4.61 | 0.0001 |
defense response | 46 | 1.37 | 2.97 | 0 |
cell surface receptor linked signal transduction | 32 | 1.28 | 2.28 | 0.001 |
sensory perception of smell | 70 | 1.25 | 2.08 | 0 |
cell proliferation | 42 | 1.24 | 2.03 | 0.0008 |
signal transduction | 222 | 1.21 | 1.79 | 0 |
regulation of apoptosis | 45 | 1.2 | 1.73 | 0 |
G-rotein coupled receptor protein signaling pathway | 166 | 1.15 | 1.32 | 0 |
regulation of transcription | 119 | 1.1 | 0.87 | 0 |
regulation of transcription DNA.dependent | 586 | 1.04 | 0.38 | 0 |
electron transport | 138 | 0.87 | -1.26 | 0 |
metabolism | 151 | 0.82 | -1.91 | 0 |
lipid metabolism | 59 | 0.79 | -2.21 | 0 |
lipid biosynthesis | 34 | 0.77 | -2.49 | 0 |
fatty acid metabolism | 32 | 0.71 | -3.15 | 0 |
(C) | Â | Â | Â | Â |
negative regulation of progression through cell cycle | 26 | 1.17 | 0.95 | 0.0022 |
anti apoptosis | 30 | 1.17 | 0.92 | 0.0015 |
metabolism | 151 | 0.92 | -0.47 | 0.0009 |
protein biosynthesis | 180 | 0.92 | -0.52 | 0 |
cell proliferation | 42 | 0.87 | -0.8 | 0.0021 |
fatty acid metabolism | 32 | 0.85 | -0.95 | 0.0015 |
rRNA processing | 29 | 0.85 | -0.97 | 0.0019 |
lipid biosynthesis | 34 | 0.84 | -1.02 | 0.0004 |
steroid biosynthesis | 20 | 0.83 | -1.09 | 0.0037 |
sterol biosynthesis | 13 | 0.8 | -1.34 | 0.0039 |
cholesterol biosynthesis | 12 | 0.79 | -1.43 | 0.003 |