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Table 2 Analysis of putative 5'UR TFBSs

From: Transcriptome analysis reveals a major impact of JAK protein tyrosine kinase 2 (Tyk2) on the expression of interferon-responsive and metabolic genes

TFBS # genes ER NC p-value
(A)     
IRF/ISRE 40 1.41 3.20 0.0011
(B)     
IRF/ISRE 40 1.53 3.99 0.0001
127 35 1.19 1.60 0.0006
CHX10 160 1.09 0.80 0.0001
IPF1 = PDX1 108 1.08 0.72 0.0010
TATA 280 1.07 0.67 0.0005
174 176 1.06 0.56 0.0009
NF-AT 519 1.03 0.25 0.0011
(C)     
115 33 1.13 0.73 0.0006
POU1F1 49 1.12 0.65 0.0019
IPF1 = PDX1 108 1.08 0.45 0.0003
FOXF2 171 1.07 0.40 0.0018
CHX10 160 1.06 0.35 0.0010
TATA 280 1.06 0.33 0.0005
  1. We assigned genes to 174 classes of putative TFBSs, either identified by their name, the major transcription factor binding to them, or their number in Xie et al. [14]. The table shows the number of genes in each TFBS class, approximate mean expression ratios (ER), mean normed coefficients (NC), and p-values from t-tests. (A) Basal differences between genotypes, (B) LPS induction in Wt, and (C) differences between genotypes in LPS induction (genotype by treatment interaction).