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Table 3 Analysis of 3'UTR regulatory sequences

From: Transcriptome analysis reveals a major impact of JAK protein tyrosine kinase 2 (Tyk2) on the expression of interferon-responsive and metabolic genes

3'UTR motif gene # ER NC p-value
(A)     
m57 110 1.04 0.39 0.0037
m11 623 0.98 -0.23 0.0026
m43 254 0.96 -0.33 0.0009
o7 207 0.96 -0.33 0.0058
(B)     
m53 42 1.30 2.60 0.0076
o34 75 1.13 1.22 0.0006
m35 54 1.13 1.18 0.0026
m103 41 1.11 1.05 0.0048
m33 119 1.11 1.04 0.0026
m95 56 1.11 1.03 0.0004
m16 213 1.10 0.99 0.0000
o25 105 1.09 0.86 0.0011
m85 82 1.09 0.84 0.0043
m2/ARE 675 1.09 0.82 0.0000
m67 164 1.07 0.68 0.0004
o18 278 1.07 0.65 0.0001
m50 108 1.07 0.64 0.0081
m100 70 1.06 0.60 0.0079
o43 142 1.05 0.49 0.0021
m30 85 1.05 0.49 0.0133
m70 136 1.05 0.48 0.0108
o12 196 1.05 0.48 0.0012
m24 332 1.05 0.47 0.0001
o15 253 1.04 0.43 0.0011
m3 481 1.04 0.43 0.0000
m20 262 1.04 0.40 0.0024
o38 142 1.04 0.38 0.0063
m29 232 1.04 0.37 0.0013
m41 224 1.04 0.36 0.0025
o32 155 1.04 0.36 0.0067
m13 1015 1.03 0.30 0.0000
m4 625 1.03 0.29 0.0000
o21 363 1.03 0.26 0.0011
m19 308 1.02 0.25 0.0028
m9 942 1.02 0.24 0.0000
m31 347 1.02 0.21 0.0018
m25 488 1.02 0.21 0.0006
m8 337 1.02 0.17 0.0077
m26 383 1.02 0.15 0.0017
m5 1175 1.01 0.06 0.0000
m1/poly-A 1938 0.95 -0.54 0.0091
(C)     
m91 66 1.1 0.56 0.0046
m13 1015 1.01 0.06 0.0016
m9 942 1.01 0.06 0.0016
  1. A total of 175 3'UTR motis were identified as described in Xie et al. [14]. The table shows the number of genes in each class of motif, approximate mean expression ratios (ER), mean normed coefficients (NC), and p-values from t-tests. (A) Basal differences between genotypes, (B) LPS induction in Wt, and (C) differences between genotypes in LPS induction (genotype by treatment interaction).