Genome-wide characterisation of the Gcn5 histone acetyltransferase in budding yeast during stress adaptation reveals evolutionarily conserved and diverged roles

Table 2 Gene Ontology categories enriched in Gcn5 dependant KCl response genes.

GO Category	Total genes†	Changed genes*	P value#
Gcn5 dependent KCl induced genes (64)
Catalytic activity	2271	33	0.016
Oxidoreductase activity	322	13	2.58e-5
Cofactor binding	156	7	0.001
Ion homeostasis	121	6	0.002
Protein folding	97	4	0.019
Gcn5 dependent KCl-repressed genes (28)
Gene expression	1438	14	0.004
Ribonucleoprotein complex biogenesis and assembly	426	9	0.001
RNA processing	448	6	0.019
Translation factor activity nucleic acid binding	58	4	1.64e-4
Iron ion binding	106	4	0.002
Protein-RNA complex assembly	140	4	0.004
Glutamine metabolic process	21	3	1.3e-4
Flocculation	11	2	0.001

† Total genes in the GO category.
*Selection criteria see methods.
# p-value from a Fisher's Extract Test (one-sided), statistical considerations are fully discussed in [44].

ISSN: 1471-2164