Table 5 GO terms significantly enriched amongst differentially expressed genes at 14 months
Gene ontology term | No. of genes | Fold Enrichment | p value |
|---|---|---|---|
RNA metabolism and regulation of gene expression | |||
protein-RNA complex assembly | 11 | 2.5 | 0.011 |
mRNA metabolic process | 23 | 1.7 | 0.012 |
mRNA processing | 21 | 1.8 | 0.014 |
gene expression | 136 | 1.2 | 0.015 |
RNA splicing | 18 | 1.8 | 0.018 |
Regulation of gene expression | 98 | 1.2 | 0.024 |
Regulation of transcription | 91 | 1.2 | 0.032 |
regulation of nucleoside, nucleotide and nucleic acid metabolic process | 92 | 1.2 | 0.040 |
transcription | 93 | 1.2 | 0.047 |
negative regulation of gene expression, epigenetic | 4 | 4.7 | 0.048 |
Nervous system development | |||
neurite morphogenesis | 14 | 2.0 | 0.018 |
neuron morphogenesis during differentiation | 14 | 2.0 | 0.018 |
axonogenesis | 13 | 2.1 | 0.019 |
neurite development | 15 | 1.8 | 0.037 |
cellular morphogenesis during differentiation | 14 | 1.8 | 0.040 |
neuron development | 16 | 1.7 | 0.045 |
Other | |||
nuclear export | 8 | 4.6 | 0.001 |
protein export from nucleus | 5 | 6.9 | 0.004 |
negative regulation of metabolic process | 23 | 1.6 | 0.029 |
phosphatidylinositol metabolic process | 4 | 5.5 | 0.032 |
nucleocytoplasmic transport | 11 | 2.1 | 0.034 |
macromolecule biosynthetic process | 41 | 1.4 | 0.034 |
nuclear transport | 11 | 2.1 | 0.036 |
negative regulation of cellular metabolic process | 20 | 1.6 | 0.046 |
phospholipid metabolic process | 11 | 2.0 | 0.047 |
heme metabolic process | 4 | 4.7 | 0.048 |