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Table 9 Genes encoding presynaptic proteins, differentially expressed in VEGFδ/δ mice

From: Downregulation of genes with a function in axon outgrowth and synapse formation in motor neurones of the VEGFδ/δ mouse model of amyotrophic lateral sclerosis

Probe ID

Gene name

Symbol

p value

FC

Reg

Time point

1456245

vesicle-associated membrane protein 3

Vamp3

0.0159

1.47

down

14 months

1423173

N-ethylmaleimide sensitive fusion protein ß

Napb

0.0021

1.59

down

14 months

1423172

N-ethylmaleimide sensitive fusion protein ß

Napb

0.0024

1.55

down

14 months

1433788

N-ethylmaleimide sensitive fusion protein ß

Napb

0.0021

1.78

down

14 months

1435396

syntaxin binding protein 6

Stxbp6

0.0290

1.46

down

5 months

1435396

syntaxin binding protein 6

Stxbp6

0.0179

1.33

down

14 months

1429314

synaptotagmin XI

Syt11

0.0274

1.47

down

5 months

1415756

SNAP-associated protein

Snapap

0.0058

1.70

down

5 months

1455304

unc-13 homolog C

Unc13c

0.0070

2.86

down

14 months

1436991

gelsolin

Gsn

0.0092

1.62

down

5 months

1419392

piccolo

Pclo

0.0267

1.47

down

14 months

1451484

synapsin I

Syn1

0.0098

1.49

down

5 months

1435511

synapsin II

Syn2

0.0146

1.74

down

5 months

1435667

regulating synaptic membrane exocytosis 1

Rims1

0.0370

1.32

up

3 months

1422880

synaptophysin-like protein

Sypl

0.0384

1.15

down

3 months

1417919

protein phosphatase 1, regulatory subunit 7

Ppp1r7

0.0256

1.30

down

5 months

1433691

protein phosphatase 1, regulatory subunit 3C

Ppp1r3c

0.0218

1.49

down

5 months

1440285

protein phosphatase 1, regulatory subunit 9A

Ppp1r9a

0.0063

1.24

down

5 months

1452046

protein phosphatase 1, catalytic subunit, gamma

Ppp1cc

0.0276

1.38

down

5 months

1434895

protein phosphatase 1, regulatory subunit 13B

Ppp1r13b

0.0280

1.32

down

14 months

1456072

protein phosphatase 1, regulatory subunit 9A

Ppp1r9a

0.0217

1.32

down

14 months

1440285

protein phosphatase 1, regulatory subunit 9A

Ppp1r9a

0.0304

1.22

down

14 months

1420734

protein phosphatase 1, regulatory subunit 3F

Ppp1r3f

0.0102

1.17

down

14 months

1456606

phosphatase and actin regulator 1

Phactr1

0.0196

1.35

down

5 months

1455101

phosphatase and actin regulator 2

Phactr2

0.0489

1.66

down

5 months

1455101

phosphatase and actin regulator 2

Phactr2

0.0463

1.41

down

14 months