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Figure 3 | BMC Genomics

Figure 3

From: The ancient mammalian KRAB zinc finger gene cluster on human chromosome 8q24.3 illustrates principles of C2H2 zinc finger evolution associated with unique expression profiles in human tissues

Figure 3

Evolutionary changes in the ZNF252 ortholog group. Gene (A) and protein domain (B) organization depicted for the mammalian ZNF252 ortholog group (see Additional files 1 and 2 for sequences). For legend see Figure 2. Gaps in the genomic sequence are indicated by --nnn-. An asterisk indicates a stop codon. Dashed lines in (B) illustrate potential coding sequences that are probably untranslated because of stop codons. The tilde denotes a shift in the open reading frame. The presumably longest predicted ORF are shown as black bars under the protein domain depiction. Species abbreviations: hs, Homo sapiens; pt, Pan troglodytes; mmul, Macaca mulatta; cf, Canis familiaris; mondom, Monodelphis domestica.

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