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Figure 4 | BMC Genomics

Figure 4

From: Drug target prediction and prioritization: using orthology to predict essentiality in parasite genomes

Figure 4

Prioritizing essential nematode drug targets. This flow diagram outlines our approach to drug target prediction and prioritization for parasitic nematodes. Some steps are clear "keep or reject" decisions because the genes failing these criteria are either not easily amenable to further development or have an unacceptable probability of being essential. Other steps are used to quantitatively refine the weighting to produce a ranked list of essential drug targets.

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BMC Genomics

ISSN: 1471-2164

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