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Table 3 Localization predictions for proteins encoded by preferentially expressed transcripts in B. pahangi microfilariae.

From: Differential transcript expression between the microfilariae of the filarial nematodes, Brugia malayi and B. pahangi

Pub Locus Annotation SignalP TargetPa PSORTII ProtComp
Bm1_49810 Conserved hypothetical protein Signal mitochondria (5) CY PM
Bm1_44755 RE21922p, putative Signal mitochondria (5) ER PM
Bm1_23875 Hypothetical protein Signal mitochondria (5) GO ER
Bm1_03995 Serpin (BmSERPIN), putative Signal secreted (1) ER ER
Bm1_02070 Serpin, putative Signal secreted (1) ER ER
Bm1_32890 Histidine acid phosphatase family protein Signal secreted (1) ER MT
Bm1_07905 Metallophosphoesterase 1, putative Signal secreted (1) ER PM
Bm1_42865 Brugia malayi antigen, putative Signal secreted (1) EX EX
Bm1_40635 Conserved hypothetical protein Signal secreted (1) EX EX
Bm1_37310 FKBP-type peptidyl-prolyl cis-trans isomerase-13, BmFKBP-13 Signal secreted (1) EX EX
Bm1_47735 Lipase family protein Signal secreted (1) EX EX
Bm1_49635 Protein C17H12.11, putative Signal secreted (1) EX EX
Bm1_53990 Zinc finger, C2H2 type family protein Signal secreted (1) EX NU
Bm1_39915 Transthyretin-like family protein Signal secreted (2) CY EX
Bm1_00735 Hypothetical protein Signal secreted (2) CY NU
Bm1_50605 Ribonuclease T2 family protein Signal secreted (2) ER EX
Bm1_28420 DnaJ protein, putative Signal secreted (2) EX EX
Bm1_56195 Transforming growth factor b homolog, putative Signal secreted (2) EX EX
Bm1_33495 Probable protein disulfide isomerase A6 precursor, putative Signal secreted (3) EX ER
Bm1_25940 Serpin, putative Signal unknown (2) ER EX
Bm1_35905 Hypothetical protein Signal unknown (3) ER PM
Bm1_43565 MBOAT family protein Signal unknown (3) PM ER
Bm1_18845 GRIM-19 protein Signal unknown (4) CY GO
Bm1_37335 Ankyrin-related unc-44, putative Signal unknown (4) NU EX
Bm1_40630 Hypothetical protein Signal unknown (5) CY PM
Bm1_24145 ABC1 family protein Signal unknown (5) ER PE
Bm1_29610 Hypothetical protein Signal unknown (5) EX NU
  1. a Values in parentheses from TargetP results represent the reliability class (RC), from 1 to 5, where 1 indicates the strongest prediction. For PSORTII, location with the highest percentage score is shown. For ProtComp, the integral prediction of protein location is shown. CY, cytoplasm; ER, endoplasmic reticulum; EX, extracellular; GO, Golgi apparatus; NU, nuclear; PE, peroxisome; PM, plasma membrane; MT, mitochondria.