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Table 4 Localization predictions of proteins encoded by preferentially expressed transcripts in B. malayi microfilariae.

From: Differential transcript expression between the microfilariae of the filarial nematodes, Brugia malayi and B. pahangi

Pub Locus Annotation SignalP TargetPa PSORTII ProtComp
Bm1_12070 K+ channel tetramerisation domain containing protein Signal mitochondria (5) GO PM
Bm1_02255 Zinc finger, C2H2 type family protein Signal mitochondria (5) NU NU
Bm1_14030 Hypothetical protein Signal secreted (1) CY EX
Bm1_56305 Leucyl aminopeptidase, putative Signal secreted (1) ER EX
Bm1_50670 Potassium channel chain n2P18 homolog, putative Signal secreted (1) ER EX
Bm1_30525 Hypothetical protein Signal secreted (1) EX EX
Bm1_33955 Hypothetical protein Signal secreted (1) EX EX
Bm1_19100 Major microfilarial sheath protein precursor, putative Signal secreted (1) EX EX
Bm1_10870 Zinc finger, C2H2 type family protein Signal secreted (1) NU CY
Bm1_09090 Zinc finger, C2H2 type family protein Signal secreted (1) NU ER
Bm1_55930 Nematode cuticle collagen N-terminal domain containing protein Signal secreted (1) NU EX
Bm1_18365 Zinc finger, C2H2 type family protein Signal secreted (1) NU EX
Bm1_22980 Zinc finger, C2H2 type family protein Signal secreted (1) NU EX
Bm1_35265 Zinc finger, C2H2 type family protein Signal secreted (1) NU EX
Bm1_34385 Hypothetical protein Signal secreted (1) NU GO
Bm1_04225 Zinc finger, C2H2 type family protein Signal secreted (1) NU GO
Bm1_11185 Zinc finger, C2H2 type family protein Signal secreted (1) NU GO
Bm1_13985 Zinc finger, C2H2 type family protein Signal secreted (1) NU GO
Bm1_47425 Zinc finger, C2H2 type family protein Signal secreted (1) NU GO
Bm1_21005 Hypothetical protein Signal secreted (1) NU MT
Bm1_22820 Hypothetical protein Signal secreted (2) CY EX
Bm1_45345 Hypothetical 31.4 kDa protein T19C3.2 chromosome III, putative Signal secreted (2) ER EX
Bm1_22110 Hypothetical protein Signal secreted (2) ER PM
Bm1_33830 Prismalin-14, putative Signal secreted (2) MT EX
Bm1_23300 Zinc finger, C2H2 type family protein Signal secreted (2) NU EX
Bm1_03355 Hypothetical protein Signal secreted (3) CY EX
Bm1_08145 Zinc finger, C2H2 type family protein Signal secreted (3) NU NU
Bm1_44495 Hypothetical protein Signal secreted (4) CY EX
Bm1_00295 Hypothetical protein Signal secreted (4) ER PM
Bm1_47450 Conserved hypothetical protein, putative Signal secreted (4) GO EX
Bm1_31055 RNA recognition motif containing protein, putative Signal secreted (4) NU EX
Bm1_15340 Zinc finger, C2H2 type family protein Signal secreted (4) NU NU
Bm1_03710 Zinc finger, C2H2 type family protein Signal secreted (5) NU EX
Bm1_05155 Zinc finger, C2H2 type family protein Signal secreted (5) NU EX
Bm1_01300 Alpha amylase, catalytic domain containing protein Signal unknown (1) CY EX
Bm1_25950 Hypothetical protein Signal unknown (2) ER EX
Bm1_44655 Fukutin, putative Signal unknown (2) ER PM
Bm1_01585 Fatty acid elongation protein 3, putative Signal unknown (5) ER EX
Bm1_56360 Nematode cuticle collagen N-terminal domain containing protein Signal unknown (5) NU EX
  1. a Values in parentheses from TargetP results represent the reliability class (RC), from 1 to 5, where 1 indicates the strongest prediction. For PSORTII, location with the highest percentage score is shown. For ProtComp, the integral prediction of protein location is shown. CY, cytoplasm; ER, endoplasmic reticulum; EX, extracellular; GO, Golgi apparatus; NU, nuclear; PE, peroxisome; PM, plasma membrane; MT, mitochondria.