|
genes
|
Number
|
ΔΔct (1 h/control)
|
ΔΔct (3 h/control)
|
ΔΔct (6 h/control)
|
ΔΔct (12 h/control)
|
|---|
|
ACSL1
|
12
|
1.58 ± 1.72
|
2.21 ± 3.81
|
0.47 ± 0.55#
|
0.71 ± 1.46
|
|
ALDH8A1
|
12
|
1.26 ± 0.62
|
5.16 ± 9.96
|
16.47 ± 40.57
|
2.78 ± 3.74
|
|
CMTM8
|
12
|
4.24 ± 5.47
|
60.46 ± 127.18
|
48.60 ± 111.88
|
62.93 ± 106.90
|
|
COLEC11
|
12
|
0.73 ± 0.29#
|
4.04 ± 2.35#*
|
3.27 ± 4.40
|
1.50 ± 2.00&
|
|
COLEC12
|
12
|
1.19 ± 0.54
|
3.86 ± 3.41#*
|
2.44 ± 2.77
|
6.59 ± 12.03
|
|
DPP4
|
12
|
0.87 ± 0.60
|
11.64 ± 6.76#*
|
14.91 ± 14.25#*
|
86.16 ± 218.29
|
|
FBXO3
|
12
|
1.79 ± 1.59
|
2.13 ± 1.91
|
1.64 ± 1.54
|
1.09 ± 0.72
|
|
FN3K
|
12
|
1.60 ± 1.98
|
3.38 ± 2.88#
|
2.01 ± 1.96
|
2.20 ± 3.57
|
|
GPD1L
|
12
|
2.61 ± 3.59
|
0.76 ± 0.83#
|
0.35 ± 0.30#
|
1.25 ± 3.02
|
|
HLF
|
12
|
1.49 ± 1.39
|
8.15 ± 10.11*#
|
4.26 ± 5.27
|
3.72 ± 5.31
|
|
KLB
|
12
|
1.01 ± 0.51
|
1.93 ± 1.11*#
|
2.93 ± 5.05
|
1.58 ± 1.91
|
|
MAP2K6
|
12
|
2.61 ± 1.75#
|
31.29 ± 90.44
|
0.94 ± 1.188*
|
1.40 ± 2.07
|
|
MPDZ
|
12
|
3.02 ± 2.23#
|
6.28 ± 4.92#
|
3.96 ± 5.98
|
5.11 ± 6.11
|
|
MTAP
|
12
|
1.77 ± 0.74#
|
11.75 ± 31.48
|
3.81 ± 8.55
|
1.56 ± 1.56
|
|
MSRB2
|
12
|
1.77 ± 1.60
|
7.07 ± 5.81#*
|
2.38 ± 2.35&
|
3.34 ± 3.52#
|
|
ORMDL1
|
12
|
1.15 ± 0.91
|
2.85 ± 1.81#*
|
1.57 ± 0.86&
|
1.23 ± 0.50&
|
|
POLG2
|
12
|
0.71 ± 0.51
|
5.74 ± 9.951
|
3.07 ± 3.28*
|
1.46 ± 0.84*
|
|
STARD5
|
12
|
1.39 ± 1.20
|
2.58 ± 5.52
|
2.09 ± 2.91
|
2.52 ± 1.03#*
|
|
PARD3
|
12
|
1.24 ± 1.50
|
6.74 ± 11.47
|
3.83 ± 4.79
|
2.05 ± 2.39
|
|
SLC29A1
|
12
|
0.82 ± 0.44
|
1.75 ± 1.35*
|
1.16 ± 1.71
|
0.33 ± 0.29#*&
|
|
SOX5
|
12
|
0.91 ± 0.65
|
1.56 ± 0.63#*
|
0.85 ± 0.52&
|
3.25 ± 3.84
|
|
TERT
|
12
|
0.82 ± 0.70
|
2.71 ± 2.52#*
|
1.89 ± 2.55
|
1.09 ± 2.22
|
|
CAR5A
|
12
|
1.87 ± 2.61
|
2.56 ± 3.16
|
0.54 ± 0.57#
|
0.45 ± 0.63#&
|
|
FASTKD1
|
12
|
0.38 ± 0.26#
|
1.75 ± 1.35*
|
0.95 ± 0.50*
| 0.46 ± 0.30#&◇ |
|
PDE7B
|
12
|
0.64 ± 0.40#
|
1.39 ± 2.18
|
0.44 ± 0.33#
|
0.59 ± 0.33#
|
|
FASTKD1
|
12
|
0.96 ± 0.96
|
1.90 ± 1.04#*
|
0.63 ± 0.44#&
|
0.60 ± 0.49#&
|
- #: Compared with 0 h, the difference was significant (p < 0.05)
- *: Compared with 1 h, the difference was significant (p < 0.05)
- &: Compared with 3 h, the difference was significant (p < 0.05)
- ◇: Compared with 6 h, the difference was significant (p < 0.05)
- Compared with normal controls, the expression of most of the 26 genes showed a statistical significant change (p < 0.05). Expressions of PARD3, ALDH8A1, CMTM8 and FBXO3 were also higher than those of normal controls, but there was no statistical significance (p > 0.05)
