Figure 4

Scenario for the multiplication of pseudogenes in Y. lipolytica. a) Rectangle represents the functional gene, dashed rectangles represent its corresponding pseudogenes. The tree topology is obtained by maximum likelihood reconstruction [69] based on the aligned nucleic acid sequences (branch lengths ignored). The emergence of frameshift mutations (!) and in-frame stop-codons (*) are indicated above corresponding branches. b) Alignment of the translation products of YALI0A14927g and its pseudogenes obtained by MUSCLE. frameshift mutations (!) and in-frame stop-codons (*) are boxed.