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Table 4 CGD metabolic pathways that show evidence of gene clustering.

From: Analysis of gene evolution and metabolic pathways using the Candida Gene Order Browser

  #Genes SC5314 WO1 Cdub Ctro Cpar Lelo Dhan Psti Pgui Clus
Histidine, purine and pyrimidine biosynthesis 41 7 7 7 5 4 4 - 3 4 -
Aerobic respiration (cyanide sensitive) 14 3 3 3 3 2 3 3 3 2 2
Aerobic respiration (cyanide insensitive) 8 2 2 2 2 2 - - - - -
2-keto glutarate dehydrogenase complex 3 2 2 2 2 - - - 2 - -
N-acetylglucosamine degradation 3 3 3 3 3 3 3 3 3 3 3
Methylglyoxal pathway 12 2 2 2 2 2 2 - - - -
Sphingolipid metabolism 8 - - - - - - - - 2 -
Ergosterol biosynthesis 21 - - - - - - 2 - 2 2
Biotin biosynthesis 4 4 4 - 3 - - 2 - - -
NAD salvage pathway 4 - - - 2 - - - - - -
Tetrapyrrole biosynthesis 4 2 2 2 2 - - - 2 - -
Pantothenate and coA biosynthesis 11 2 2 2 2 2 2 2 2 2 2
Starch degradation 7 - - - - - - - - - 2
Lipid-linked oligosaccharide biosynthesis 8 - - - 2 2 3 2 3 2 -
Arginine degradation (arginase pathway) 5 2 2 2 - - - 2 2 2 2
Lysine biosynthesis 6 - - - 2 - - - - - -
Superpathway of glycine biosynthesis 5 - - - - 2 - - - - -
Biosynthesis of phe/tyr/trp 13 - - - - - 2 - - - -
Superpathway of glycine biosynthesis 5 - - - - 5 - - - - -
Acrylonitrile degradation 4 - - - 2(2T) 2(2T) 2(2T) - 2(2T) - -
Galactose degradation 5 4(2D) 4(2D) 4(2D) 4(2D) 4(2D) 4(2D) 4(2D) 4(2D) 4(2D) 4(2D)
tRNA charging pathway 35 13(6D) 13(6D) 13(6D) 10(2D) 7(4D) 9(6D) 9(4D) 13(6D) 9(4D) 5(4D)
Fatty acid oxidation pathway 14 4(4D) 4(4D) 2(2D) 4(4D) 4(4D) - 2(2D) 2(2D) 2(2T) 2(2T)
Glutathione-glutaredoxin redox reactions 9 5(3D, 3D) 5(2D,2T)* 6(3D,3T) 3(3T) 4(4T) 3(3T) 2(2T) 2(2T) 3(3T) 2(2D)
Isoleucine & phenylalanine degradation 12 2(2T) 2(2T) - - - - - - - -
Removal of superoxide radicals 7 2(2T) 2(2T) 2(2T) - - - - - - -
  1. Superscript numerals in parenthesis refer to the numbers of genes that are either paralogs D or tandem duplicates T.