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Table 3 Genetic variation in exon 2 sequences of the DRB gene observed for 1,407 rodent samples from 24 species and 11 genera.

From: A 454 multiplex sequencing method for rapid and reliable genotyping of highly polymorphic genes in large-scale studies

Rodent Genera Number of DRB copy amplified Number of analysed samples Replicates Genotyped (p= 0.999) Heterozygotes genotyped Number of variant Mean number of sequences per variant
    Nb % Nb % Nb %   
Pool A           
Myodes 2 650 33 5.1 602 93 495 82.2 71 834
Arvicola 1 49 2 4.1 49 100 36 73.5 13 324
Microtus 1 40 2 5.0 36 90 29 80.6 7 403
Apodemus 1 44 3 6.8 42 95 39 92.9 50 70
Pool B           
Rattus 1 417 19 4.6 388 93 248 63.9 110 233
Mus 1 147 8 5.4 134 91 110 82.1 53 171
Niviventer 1 78 5 6.4 44 56 9 20.5 15 172
Bandicota 1 58 4 6.9 51 88 39 76.5 21 154
Berylmys 1 37 4 10.8 36 97 25 69.4 19 122
Leopoldamys 1 24 1 4.2 21 88 14 66.7 12 121
Maxomys 4 22 2 9.1 4 18 4 100.0 21 37
Total   1,566 83 5.3 1,407 90 1,048 74.5 392 277
  1. The confidence level used for validating genotypes was fixed at 10-3.