Table 3 Top 20 brain-specific genes.
From: Comparison and consolidation of microarray data sets of human tissue expression
Entrez GeneID | Consolidated Rank | Rosetta1 MAX | Rosetta2 MAX | Stanford MAX | Genealtas MAX | Locuslink Symbol | Description |
|---|---|---|---|---|---|---|---|
2670 | 1 | 5.25 | 4.90 | 5.02 | 3.48 | GFAP | Glial fibrillary acidic protein, a major intermediate filament proteins of astrocytes |
11075 | 2 | 4.57 | 4.45 | 4.53 | 5.04 | STMN2 | Stathmin-like 2, a neuronal growth-associated protein |
2596 | 3 | 6.38 | 5.69 | 4.16 | 2.75 | GAP43 | Growth associated protein 43, regulates growth of axons during development and regeneration |
4747 | 4 | 4.86 | 3.47 | 3.33 | 3.75 | NEFL | Neurofilament, light polypeptide, a major constituent of the axoskeleton |
5354 | 5 | 5.13 | 2.72 | 4.30 | 4.45 | PLP1 | Proteolipid protein 1, predominant myelin protein present in CNS |
5375 | 6 | 4.47 | 4.95 | 2.97 | 2.09 | PMP2 | Peripheral myelin protein 2 |
9568 | 7 | 3.41 | 3.89 | 4.25 | 2.19 | GABBR2 | Gamma-aminobutyric acid (GABA) B receptor 2 |
9118 | 8 | 4.06 | 4.02 | 3.24 | 1.79 | INA | Internexin neuronal intermediate filament protein alpha |
1759 | 9 | 3.24 | 3.35 | 2.93 | 2.69 | DNM1 | Dynamin 1, involved in clathrin-mediated endocytosis |
6456 | 10 | 3.57 | 3.45 | 2.46 | 2.51 | SH3GL2 | SH3-domain GRB2-like 2, Endophilin 1, mediator of synaptic vesicle formation |
6616 | 11 | 5.54 | 3.25 | 1.52 | 4.17 | SNAP25 | Synaptosomal-associated protein 25 kDa, a SNARE protein required for neuronal exocytosis |
29114 | 12 | 4.10 | 3.09 | 3.80 | 2.00 | NP22 | Neural protein 22 |
4155 | 13 | 5.10 | 3.46 | 1.30 | 4.79 | MBP | Myelin basic protein, major constituent of myelin sheath of oligodendrocytes and Schwann |
11076 | 14 | 2.67 | 3.43 | 2.84 | 2.27 | TPPP | Tubulin polymerization promoting protein |
6285 | 15 | 2.87 | 2.21 | 3.54 | 3.64 | S100B | S100 calcium binding protein B, glial-derived protein serving as neurotrophic factor and neuronal survival protein |
4741 | 16 | 2.97 | 2.78 | 2.55 | 2.52 | NEFM | Neurofilament, medium polypeptide 150 kDa |
1463 | 17 | 3.25 | 5.22 | 1.54 | 1.97 | NCAN | Neurocan, involved in the modulation of cell adhesion and migration. |
3797 | 18 | 3.86 | 2.98 | 2.56 | 1.56 | KIF3C | Neurospecific KIF3C kinesin family member 3 |
29106 | 19 | 4.83 | 2.81 | 2.50 | 1.51 | SCG3 | Secretogranin III, a neuroendocrine secretory protein |
81551 | 20 | 3.44 | 2.41 | 1.85 | 2.67 | STMN4 | Stathmin-like 4, regulation of the microtubule cytoskeleton |