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Figure 4 | BMC Genomics

Figure 4

From: In silico and biological survey of transcription-associated proteins implicated in the transcriptional machinery during the erythrocytic development of Plasmodium falciparum

Figure 4

Potential interactions observed by in silico and yeast two hybrid approach between the GTF and ApiAP2. TAP candidates eliciting interactions from in silico [53] and Y2D data [54] were extracted from PlasmoDB and only the proteins for which an interaction was inferred are presented. The two networks were merged and graphically represented using Cytoscape 2.6 http://www.cytoscape.org. Red circle stands for general transcription factors, yellow for chromatin-related proteins, green for specific transcription factors and blue for partners. Grey lines represent the in silico interactions and pink lines those proposed by the two-hybrid experiment. A. Interaction network for the preinitiation complexe. B. Interaction network for the ApiAP2 TF. For the complete interaction network see Additional file 5.

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