Overall approach for extraction of endothelial restricted genes. A) Unsupervised Pearson Correlation based cluster of different EC and non-EC arrays after normalizing the data. ECs (HMVEC, HUVEC, HPVEC, HAEC, and HCEAC) form separate clusters from non-ECs (HSAMC, B Cells, T Cells). In most of cases biological replicates of each cell type have better correlation with each other than with other cell types. B) Venn diagram indicating overlap between microvascular, arterial and venous endothelial differentially expressed genes obtained from the primary analysis C) Schematic representation of the approach for identifying the genes with EC-restricted expression (EC-restricted) D) Venn diagram depicting the overlap between microvascular, arterial and venous endothelial restricted transcripts.