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Table 1 Gene differentially regulated by dystrophin deficiency and cited in the text

From: Transcriptomic analysis of dystrophin RNAi knockdown reveals a central role for dystrophin in muscle differentiation and contractile apparatus organization

Entrez ID

Gene Symbol

Gene Name

Fold Change

Adjusted p value

66211

Rpl3l

ribosomal protein l3-like

-6.3

3.80E-08

13405

Dmd

dystrophin, muscular dystrophy

-3.7

9.54E-08

19293

Pvalb

parvalbumin

-6.1

9.54E-08

78785

Clip4

CAP-GLY domain containing linker protein family, member 4

-3

9.54E-08

16716

Ky

kyphoscoliosis peptidase

-4.1

1.48E-07

59011

Myoz1

myozenin 1

-3.6

2.46E-07

19130

Prox1

prospero-related homeobox 1

3

2.55E-05

233199

Mybpc2

myosin binding protein c, fast-type

-2.3

3.81E-05

12335

Capn3

calpain 3

-2.1

3.82E-05

18682

Phkg1

phosphorylase kinase gamma 1

-3.9

3.82E-05

14403

Gabrd

gamma-aminobutyric acid (gaba-a) receptor, subunit delta

-4.2

8.94E-05

243912

Hspb6

heat shock protein, alpha-crystallin-related, b6

-1.9

1.77E-04

140781

Myh7

myosin, heavy polypeptide 7, cardiac muscle

2.7

2.10E-04

21393

Tcap

titin-cap

-1.7

2.45E-04

76469

Cmya5

cardiomyopathy associated 5

-1.8

2.74E-04

380698

Obscn

obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF

-2

3.19E-04

76884

Cyfip2

riken cdna 1500004i01 gene

-2.1

4.12E-04

12632

Cfl2

cofilin 2, muscle

-1.7

8.51E-04

100072

Camta1

calmodulin binding transcription activator 1

-1.6

8.96E-04

20266

Scn1b

sodium channel, voltage-gated, type i, beta

-1.7

9.09E-04

18642

Pfkm

phosphofructokinase, muscle

-1.5

1.10E-03

11448

Chrne

cholinergic receptor, nicotinic, epsilon polypeptide

-3.4

1.16E-03

74769

Pik3cb

phosphatidylinositol 3-kinase, catalytic, beta polypeptide

1.5

1.25E-03

12372

Casq1

calsequestrin 1

-1.6

3.27E-03

14245

Lpin1

lipin 1

-1.5

3.79E-03

109731

Maob

monoamine oxidase b

-1.5

4.95E-03

12575

Cdkn1a

cyclin-dependent kinase inhibitor 1a (p21)

-1.5

6.65E-03

14555

Gpd1

glycerol-3-phosphate dehydrogenase 1 (soluble)

-1.7

6.65E-03

19309

Pygm

muscle glycogen phosphorylase

-1.6

7.55E-03

26409

Map3k7

mitogen activated protein kinase kinase kinase 7 (Synonym Tak1)

1.5

1.22E-02

338372

Map3k9

mitogen-activated protein kinase kinase kinase 9

1.8

1.66E-02

11474

Actn3

actinin alpha 3

-1.6

1.75E-02

20661

Sort1

sortilin 1

1.6

1.82E-02

  1. This table details genes from Additional file 2 that were cited in the text. Table sorted by ascending adjusted p values. Italicized genes are those dysregulated in dystrophin siRNA treated samples versus untreated samples, but changing in the opposite direction in the GL2 siRNA treated versus untreated samples (see result section for details).