Skip to main content
Figure 2 | BMC Genomics

Figure 2

From: Copy number variation and cytidine analogue cytotoxicity: A genome-wide association approach

Figure 2

Comparison of chromosome 22 CNV regions identified using our 197 cell line samples compared with the results of previous studies in the UCSC genome browser. The Illumina 550 + 650 K (all samples combined), Illumina 550 K (CA, CEPH, HCA populations) and Illumina 650 K (AA samples) results in the diagram are from the present study, where spikes in the data indicate changes in CNV values. The "RefSeq Genes" row shows the locations of known genes in the human genome. In the "Structural Variation" tracks, green color indicates duplications, red indicates deletions, blue indicates both deletion and duplication, black represents an inversion and gray could be a gain or loss. "Conrad Dels" in the diagram are deletions detected by the analysis of SNP genotypes using the HapMap Phase I data, release 16c.1, CEU and YRI samples [11]. "Hinds Dels" are deletions observed during haploid hybridization analysis in 24 unrelated individuals from the Polymorphism Discovery Resource, selected for a SNP LD study [12]. "Iafrate CNVs" are from BAC microarray analysis of a population of 55 individuals [21]. "Locke CNVs" are CNV regions identified using array CGH in 269 HapMap individuals [22]. "McCarroll Dels" are deletions from genotype analysis, performed with HapMap Phase I data, release 16a [13]. "Redon CNVs" are from SNP and BAC microarray analysis of HapMap Phase II data [7]. "Sebat CNVs" represents oligonucleotide microarray analysis performed with a population of 20 normal individuals [7]. "Sharp CNVs" represents putative CNV regions detected by BAC microarray analysis in a population of 47 individuals [24]. The "Tuzun Fosmids" row consists of fosmid mapping sites detected by mapping paired-end sequences from a human fosmid DNA library [25].

Back to article page