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Figure 3 | BMC Genomics

Figure 3

From: Copy number variation and cytidine analogue cytotoxicity: A genome-wide association approach

Figure 3

Functional characterization for the SMYD3 candidate gene with specific siRNA knockdown. (A) Knockdown of the SMYD3 gene in human MIApaca-2 pancreatic cancer cells resulted in increased resistance to both AraC and gemcitabine as determined by MTS assay. SEM values for 3 independent experiments were so small that they are contained within the symbols. (B) Quantitative RT-PCR for SMYD3 in MIApaca-2 cells. Error bars represent SEM values for three independent experiments.

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