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Table 3 Significant associations between AraC IC50 values and CNV regions.

From: Copy number variation and cytidine analogue cytotoxicity: A genome-wide association approach

CNV ID

Permutation P-value

Chromosome: Region

Number of SNPs

Length (bp)

SNP start-SNP end

Nearest Gene(s)

chr22CNV102

0.013

chr22:24092010-24128856

5

36847

rs713878-rs84486

LRP5L

 

0.028

chr22:23999581-24091936

14

92356

rs6004527-rs713847

LRP5L

 

0.028

chr22:24135224-24239811

30

104588

rs13057190-rs2780695

LRP5L

chr2CNV10

0.016

chr2:89714801-89874746

9

159946

rs2847840-rs842164

FLJ40330

chr12CNV76

0.020

chr12:19364102-19442103

16

78002

rs12825616-rs2565666

PLEKHA5

chr1CNV7

0.035

chr1:243707190-243713984

6

6795

rs10737772-rs12121903

SMYD3,KIF26B

chr2CNV11

0.044

chr2:110243431-110315618

11

72188

rs3789735-rs17463266

NPHP1

chr12CNV83

0.047

chr12:130368913-130378451

5

9539

rs12319995-rs4759915

GPR133

  1. Association of CNV regions with the AraC phenotype.