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Table 1 Over-represented Gene Ontology terms in the lists of differentially expressed genes

From: Functional genomics of human bronchial epithelial cells directly interacting with conidia of Aspergillus fumigatus

List of Terms Up-Regulated in Positive Cells (376 genes)

GOID

Ontology

Term

P-value

GO:0000786

CC

nucleosome

9.52E-12

GO:0006334

BP

nucleosome assembly

1.19E-11

GO:0008009

MF

chemokine activity

3.10E-05

GO:0001664

MF

G-protein-coupled receptor binding

3.30E-05

GO:0006749

BP

glutathione metabolic process

3.70E-05

GO:0009611

BP

response to wounding

1.08E-03

GO:0005125

MF

cytokine activity

5.37E-03

GO:0009605

BP

response to external stimulus

5.76E-03

GO:0006954

BP

inflammatory response

1.07E-02

GO:0006955

BP

immune response

2.16E-02

List of Terms Down-Regulated in Positive Cells (513 genes)

GOID

Ontology

Term

P-value

GO:0000279

BP

M phase

5.07E-13

GO:0043229

CC

intracellular organelle

8.96E-13

GO:0022402

BP

cell cycle process

5.26E-12

GO:0005634

CC

nucleus

1.43E-11

GO:0000278

BP

mitotic cell cycle

4.51E-11

GO:0044424

CC

intracellular part

8.33E-11

GO:0048285

BP

organelle fission

1.59E-10

GO:0005694

CC

chromosome

2.54E-07

GO:0006996

BP

organelle organization

4.31E-07

GO:0007098

BP

centrosome cycle

4.49E-05

  1. Selected terms, belonging to the biological process (BP), molecular function (MF), and cellular component (CC) ontologies, are indicated, and the p-value for enrichment in the appropriate list is shown.