Functional genomics of human bronchial epithelial cells directly interacting with conidia of Aspergillus fumigatus

Table 2 Genes showing the highest fold-changes between positive and negative sorted cells

Gene Symbol	Gene Name	Fold Change	P-value
MMP1	matrix metallopeptidase 1 (interstitial collagenase)	1.69	2.94E-03
MMP3	matrix metallopeptidase 3 (stromelysin 1, progelatinase)	1.63	1.07E-02
CCL5	chemokine (C-C motif) ligand 5	1.60	3.38E-02
CCL3	chemokine (C-C motif) ligand 3	1.58	2.53E-02
ROCK1	Rho-associated, coiled-coil containing protein kinase 1	1.51	5.00E-02
GREM1	gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis)	1.50	1.01E-02
ACTN2	actinin, alpha 2	1.46	1.22E-02
FBXO32	F-box protein 32	1.43	1.64E-02
MGST1	microsomal glutathione S-transferase 1	1.43	2.73E-03
EVI2B	ecotropic viral integration site 2B	1.40	8.27E-04
LRRFIP1	leucine rich repeat (in FLII) interacting protein 1	-1.33	2.96E-02
SFTPC	surfactant protein C	-1.34	3.97E-02
C9orf100	chromosome 9 open reading frame 100	-1.35	2.14E-03
LIPE	lipase, hormone-sensitive	-1.35	2.67E-02
TERT	telomerase reverse transcriptase	-1.36	1.54E-02
MTERFD3	MTERF domain containing 3	-1.37	3.53E-03
SFTPC	surfactant protein C	-1.37	2.55E-02
KIAA0802	KIAA0802	-1.37	1.01E-02
SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3	-1.39	6.14E-04
NDE1	nudE nuclear distribution gene E homolog 1 (A. nidulans)	-1.50	2.98E-02

The fold change is the ratio of the expression level in the two conditions, with positive numbers representing up-regulation in positive samples, while negative numbers indicate down-regulation in the positive samples, compared to negative samples. The paired t-test p-value for differential expression is also shown. Probes lacking annotations were excluded from this list.