Figure 4

Log2 ratio plot of prednisolone-induced differential gene expression in wild type versus GR^dim mice. Genes on the solid black line show an equal induction of differential gene expression by prednisolone in wild type (WT) versus GR^dim mice. The black-dotted line indicates the average slope of the data and shows that the level of gene regulation in prednisolone-treated GR^dim mice is 33% of that observed in WT mice. A subset of genes that show obvious differences in the magnitude of regulation by prednisolone in WT versus GR^dim mice is highlighted, as well as genes that show equal magnitude of regulation in WT versus GR^dim mice.