Prednisolone-induced differential gene expression in mouse liver carrying wild type or a dimerization-defective glucocorticoid receptor

Table 1 CoPub keyword enrichment analysis on prednisolone-regulated genes.

Biological process	# of associated genes
Metabolism
Glucose metabolism/transport	22
Gluconeogenesis	21
Lipid metabolism/glycosylation	21
Glycolysis	14
Carbohydrate metabolism/transport	14
Amino acid metabolism/transport	13
Cell cycle and apoptosis
Apoptosis	77
Cell proliferation	72
Cell cycle	65
Cell growth and-or maintenance, cell growth	63
Homeostasis	58
Cell differentiation	49
Cell cycle arrest	37
Immune/inflammatory response
Inflammatory response	31
Acute-phase response	20

CoPub was used to calculate keyword enrichment in the set of prednisolone-regulated probe sets in wild type mice. The analysis revealed that the differential regulated genes (non-redundant set) are predominantly involved in three main processes: metabolism, cell cycle and apoptosis, and immune/inflammatory response. The right column shows the number of differential regulated genes associated with a specific enriched keyword.

ISSN: 1471-2164