Table 3 Differentially expressed genes of transcription factors (TF) and over-representation (over-rep) of TF binding sequences within each gene cluster
From: Transcriptional regulation of gene expression clusters in motor neurons following spinal cord injury
| DEG of TF | ||||
|---|---|---|---|---|
| Clusters | Gene ID | Protein ID | TF over-rep | Motifs |
| Cluster 1 | Gtf2e2 | T2EB | E2F1 | E2F1_Q3_01 |
| Nfyc | NFYC | FOXO1 | E2F1_Q2_01 | |
| Olig1 | OLIG1 | E2F1_Q6_01 | ||
| Pbx3 | PBX3 | FOXO1_01 | ||
| Tfb2m | TFB2M | FOXO1_02 | ||
| Cluster 2 | E2f5 | E2F5 | FOXO1 | FOXO1_01 |
| Morf4l1 | MO4L1 | FOXO1_02 | ||
| Cluster 3 | Aatf | AATF | FOXO1 | FOXO1_01 |
| Btf3 | BTF3 | FOXO1_02 | ||
| Klf10 | KLF10 | |||
| Cluster 4 | Arid1b | ARID1B | E2F1 | E2F1_Q3_01 |
| Gtf2ird1 | GT2D1 | FOXO1 | FOXO1_01 | |
| Irf9 | IRF9 | FOXO1_02 | ||
| Cluster 5 | Atf3 | ATF3 | ATF4 | ATF4_Q2 |
| Myc | MYC | |||
| Tceb3 | ELOA1 | |||
| Ybx1 | YBX1 | |||
| Cluster 6 | ATF4 | ATF4_Q2 | ||
| E2F1 | E2F1_Q3 | |||
| MYC | MYC_Q2 | |||
| SP1 | SP1_01 | |||
| SP1_Q2_01 | ||||
| SP1_Q4_01 | ||||
| SP1_Q6 | ||||
| SP1_Q6_01 | ||||
| Cluster 7 | E2f1 | E2F1 | ATF3 | ATF3_Q6 |
| Foxo1 | FOXO1 | ATF4 | ATF4_Q2 | |
| Gtf3c1 | TF3C1 | E2F1 | E2F1_Q3 | |
| Sp1 | SP1 | MYC | E2F1_Q3_01 | |
| SP1 | E2F1_Q4 | |||
| E2F1_Q4_01 | ||||
| E2F1_Q6 | ||||
| E2F1_Q6_01 | ||||
| MYC_Q2 | ||||
| SP1_01 | ||||
| SP1_Q2_01 | ||||
| SP1_Q4_01 | ||||
| SP1_Q6 | ||||
| SP1_Q6_01 | ||||
| Cluster 8 | Hsf4 | HSF4 | ATF3 | ATF3_Q6 |
| Tbx3 | TBX3 | ATF4 | ATF4_Q2 | |
| E2F1 | E2F1_Q3 | |||
| MYC | E2F1_Q3_01 | |||
| SP1 | E2F1_Q6 | |||
| MYC_Q2 | ||||
| SP1_01 | ||||
| SP1_Q2_01 | ||||
| SP1_Q4_01 | ||||
| SP1_Q6 | ||||
| SP1_Q6_01 | ||||
| Cluster 9 | Arid1b | ARID1B | ATF3 | ATF3_Q6 |
| Nr2f2 | COT2 | E2F1 | E2F1_Q3 | |
| Pou2f3 | PO2F3 | SP1 | E2F1_Q6 | |
| Runx3 | RUNX3 | SP1_01 | ||
| SP1_Q2_01 | ||||
| SP1_Q4_01 | ||||
| SP1_Q6 | ||||
| SP1_Q6_01 | ||||
| Cluster 10 | Atf4 | ATF4 | ATF4 | ATF4_Q2 |
| Srebf1 | SRBP1 | E2F1 | E2F1_Q3 | |
| MYC | E2F1_Q3_01 | |||
| SP1 | E2F1_Q4 | |||
| E2F1_Q4_01 | ||||
| E2F1_Q6 | ||||
| E2F1_Q6_01 | ||||
| MYC_Q2 | ||||
| SP1_01 | ||||
| SP1_Q2_01 | ||||
| SP1_Q4_01 | ||||
| SP1_Q6 | ||||
| SP1_Q6_01 | ||||
| Cluster 11 | Dmrt1 | DMRT1 | AFT3 | ATF3_Q6 |
| Gtf2h4 | GTF2H4 | E2F1 | E2F1_Q3 | |
| Zeb1 | ZEB1 | MYC | MYC_Q2 | |
| SP1 | SP1_01 | |||
| SP1_Q2_01 | ||||
| SP1_Q4_01 | ||||
| SP1_Q6 | ||||
| SP1_Q6_01 | ||||
| Cluster 12 | Nfia | NFIA | AFT3 | ATF3_Q6 |
| Nkx6-2 | NKX6-2 | E2F1 | E2F1_Q3_01 | |
| FOXO1 | E2F1_Q4_01 | |||
| E2F1_Q6 | ||||
| E2F1_Q6_01 | ||||
| FOXO1_01 | ||||