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Table 2 Ubr2 knockout testes show 5-fold reduced expression of pachytene-induced genes compared to wild type.

From: The ubiquitin-conjugating enzyme HR6B is required for maintenance of X chromosome silencing in mouse spermatocytes and spermatids

ID_REF

Gene Symbol

Log 2 day 11

log2 day 18

ratio 11/18

Log2 Ubr2 ko

Log 2 wt

ratio ko/wt

92929_at

Cyct

5,466

6,981

-1,515

9,848

11,482

-1,634

102949_g_at

Hemt1

7,008

10,551

-3,542

11,667

11,986

-0,319

93658_at

Ptpn20

3,638

6,142

-2,504

9,403

11,482

-2,079

93140_at

Tsx

6,571

8,912

-2,341

11,063

11,162

-0,099

92732_at

Adam2

1,868

8,318

-6,450

8,598

11,525

-2,927

101864_at

Actl7b

3,379

8,461

-5,083

6,267

8,358

-2,091

99995_at

Cetn1

3,573

8,130

-4,557

6,715

10,220

-3,505

98334_at

Crtam

0,963

5,053

-4,090

4,426

7,084

-2,657

161398_at

Dnahc8

4,075

9,146

-5,072

9,849

11,791

-1,942

160219_r_at

Meig1

1,233

6,090

-4,857

10,418

12,178

-1,761

101388_at

Pgk2

2,379

6,064

-3,685

3,770

8,484

-4,714

99326_at

Pla2g2c

6,712

8,569

-1,857

7,098

8,331

-1,233

101938_at

Pabpc2

5,849

9,399

-3,550

6,391

9,510

-3,119

93207_at

Acr

3,739

7,684

-3,945

6,097

8,689

-2,592

99542_at

Pdha2

7,661

11,078

-3,417

10,434

11,366

-0,932

99531_at

Syngr4

5,309

8,498

-3,189

8,658

10,180

-1,522

100358_s_at

Tcp10a/c

5,609

9,042

-3,433

5,171

9,343

-4,172

103058_f_at

Tcp10a/b/c

1,000

8,203

-7,203

5,689

10,602

-4,912

97381_s_at

Tcp11

5,642

9,575

-3,933

7,055

9,709

-2,654

93955_at

Zpbp

4,961

7,196

-2,235

7,822

9,488

-1,665

100526_f_at

Adam3

2,935

7,698

-4,763

5,518

9,798

-4,280

104238_at

Art5

6,036

6,990

-0,954

5,873

6,177

-0,304

92911_at

Ccna1

4,612

5,957

-1,345

4,961

7,436

-2,475

92198_s_at

Daf2

5,081

6,870

-1,789

4,466

7,113

-2,646

97480_f_at

Dnajb3

7,828

10,902

-3,075

6,795

9,034

-2,239

102795_at

Mesp1

4,225

6,013

-1,788

5,869

8,299

-2,430

161033_at

Papolb

4,717

6,695

-1,978

6,181

9,108

-2,928

102244_at

Tesp1

4,217

5,044

-0,827

4,435

7,249

-2,813

   

Average

-3,321

 

Average

-2,380

  1. Expression of pachytene-induced spermatogenesis genes at postnatal day 11 and day 18 of testis development [46], and at postnatal day 16 in wild type and Ubr2 knockout testis [44]. The ratios of the Log2 values of gene expression in total testis between day 11 and day 18 of wild type and between Ubr2 knockout and wild type testes are shown. The bottom row shows the average Log2 values of the ratios between day 11 and day 18 and between wild type and Ubr2 knockout testes.