ROC curve analysis. Black: tiling array. Red: RNA-Seq with all 32 million reads. It is evident that the RNA-Seq substantially outperforms the tiling array with consistently higher sensitivity at lower FPR. Remaining curves are for RNA-Seq with only a subset of reads utilized. At an FPR = 0.05, just 4 million reads (blue) are required to attain the same sensitivity as two tiling array replicates.