Detection-resolution trade-off. Figure 2: The detection probability, P
(left-axis), increases with increased sequencing (N), as well as insert-length (L). The expected resolution-ambiguity, |E(Θ
)| (right-axis), increases with increasing insert-length L. The bottom x-axis shows total number of reads (N) while the top x-axis shows the corresponding sequence coverage (with 50 bp paired reads relative to the human genome). □' and '●' correspond to the expected and observed values, respectively, for specific values of N and L.