Expression of a retinoic acid signature in circulating CD34 cells from coronary artery disease patients

BMC Genomics

Table 4 Expression of HOX genes is enriched in CD34+ cells.

	CD34	CD14		Macrophages		CD4		average
	avg expr	avg expr	q-value	avg expr	q-value	avg expr	q-value	Fold Change
HOXA5	2117	12	0.0	12	0.0	7	0.0	279.1
HOXA9	1073	30	0.0	18	0.0	10	0.0	76.7
HOXB5	266	19	0.0	18	0.0	18	0.0	16.6
HOXA3	92	7	0.0	7	0.0	7	0.0	15.2
HOXA10	96	12	0.0	11	0.0	10	0.0	9.4
HOXC4	173	23	0.0	24	0.0	37	0.0	7.4
HOXB4	83	14	0.0	12	0.0	55	0.0	5.6
HOXA6	213	77	0.0	63	0.0	82	0.0	3.6
HOXB2	301	131	0.0	202	0.0	752	0.0	1.6
HOXC13	115	186	0.0	204	0.0	137	1.2	-1.3

The average transcript expression level of the individual HOX genes is shown for each cell type. q-values indicate the significance of differential expression compared to CD34+ cells (generated by SAM[11]). The last column indicates the average fold change of the expression of HOX genes in CD34+ cells compared to each of the other cell types, in a paired analysis (23 pairs, and 3 comparisons).

ISSN: 1471-2164