Tir
|
MMU
| |
F21,7
|
F6 AIL2,
|
F12 AIL3
|
---|
Tir 1
|
17
|
Map Location (cM)
|
~14
|
17.9 cM
|
ND
|
| |
CI (cM)
|
ND
|
0.9 cM
|
ND
|
| |
Effect (days)
|
33.5
|
38.8
|
30.0
|
| |
PVar (%)
|
11.8
|
19.6
|
ND
|
Tir2
|
5
|
Map Location (cM)
|
~20
|
45
|
41
|
| |
CI (cM)
|
ND
|
12
|
1
|
| |
Effect (days)
|
22
|
14.7
|
8.9
|
| |
PVar (%)
|
5.3
|
3.3
|
4.5
|
Tir 3a
|
1
|
Map Location (cM)
| |
59.7
|
67
|
| |
CI (cM)
| |
1.8
|
6
|
| |
Effect (days)
| |
14.45
|
11.33
|
| |
PVar (%)
| |
2.6
|
6.7
|
Tir 3b
|
1
|
Map Location (cM)
|
73
|
73
|
76
|
| |
CI (cM)
|
ND
|
10
|
7
|
| |
Effect (days)
|
32
|
17.3
|
11.3
|
| |
PVar (%)
|
8.9
|
4.1
|
7.9
|
Tir 3c
|
1
|
Map Location (cM)
| |
94
|
86
|
| |
CI (cM)
| |
8
|
2
|
| |
Effect (days)
| |
13.4
|
12.1
|
| |
PVar (%)
| |
2.3
|
8.6
|
- The most likely map locations (cM) are given as distances in cM from the telomere. Effect, difference between alternative homozygous genotypes (additive effect) in days4; CI, 95% confidence intervals for QTL map location in cM5; PVar, proportion of phenotypic variance explained by each of the Tir loci6.
- 1 Data from [7]; Mean of BALB/cJ × C57BL/6J and A/J × C57BL/6J.
- 2 Data from [16, 19].
- 3 Generated from A/J × C57BL/6J and fixed for MMU17 A/J (susceptible) allele.
- 4 For F12 AIL, dominance effects are Tir 2, 4.5; Tir 3a, -1.2; Tir 3b, -5.7; Tir 3c, -5.0.
- 5 For F12 AIL, flanking markers defining the most likely interval containing the QTL are: Tir 2, D5MIT258-58; Tir 3a, D1MIT94-140; Tir 3b, D1MIT288-105; Tir 3c, D1MIT107-58.
- 6 For F12 AIL, LOD scores are: Tir 2, 3.81; Tir 3a, 4.49; Tir 3b, 3.48; Tir 3c, 3.18.
- 7 Tir 3 mapped as a single locus in the F2 experiment.