Figure 2
From: Comprehensive survey of human brain microRNA by deep sequencing
Conservation of human annotated and putative miRNA. The distribution of average sequence conservation scores (phastCon scores) based on alignment of 18 placental mammalian genomes within annotated human miRNA (Am/green), novel putative miRNA that passed our pipeline, excluding the ncRNA-derived miRNA (Pm/red), and the background phastCon scores distribution (Bg/grey) based on 1,000 simulations (see Methods for details). The error bars show 95% confidence interval of the background phastCon scores distribution. Shown are the proportions (A) and the numbers (B) of miRNA in each of the 10 phastCon score bins (between 0 and 1, from the least conserved to the most conserved, divided into equal intervals).