Table 2 Usage (%) of nucleotides adjacent to substitutions occurring at three codon positions.
From: Patterns of nucleotides that flank substitutions in human orthologous genes
Category | Site | 1st | 2nd | 3rd | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Â | Â | Entropy | A | C | G | T | Entropy | A | C | G | T | Entropy | A | C | G | T |
C→T | -1 | 0.096 | 18.2 | 39.9 | 27.0 | 14.9 | 0.027 | 30.7 | 24.0 | 29.9 | 15.4 | 0.030 | 30.5 | 31.1 | 19.5 | 19.0 |
| Â | 1 | 0.323 | 7.3 | 22.4 | 21.2 | 49.2 | 0.159 | 16.2 | 21.5 | 47.0 | 15.3 | 0.238 | 18.0 | 17.1 | 52.6 | 12.3 |
G→A | -1 | 0.231 | 13.1 | 50.8 | 18.5 | 17.6 | 0.392 | 26.3 | 55.6 | 12.8 | 5.3 | 0.152 | 27.0 | 42.1 | 10.7 | 20.3 |
| Â | 1 | 0.095 | 20.1 | 27.2 | 16.3 | 36.3 | 0.050 | 15.7 | 29.4 | 30.2 | 24.7 | 0.068 | 18.0 | 26.1 | 38.1 | 17.8 |
A→G | -1 | 0.170 | 22.8 | 46.3 | 13.1 | 17.9 | 0.229 | 43.7 | 33.1 | 17.2 | 6.0 | 0.272 | 28.3 | 49.4 | 8.7 | 13.6 |
| Â | 1 | 0.232 | 14.2 | 24.0 | 15.1 | 46.7 | 0.100 | 15.4 | 20.8 | 27.4 | 36.5 | 0.041 | 19.0 | 22.0 | 34.4 | 24.6 |
T→C | -1 | 0.022 | 28.4 | 30.1 | 25.3 | 16.2 | 0.119 | 41.8 | 17.3 | 28.9 | 11.9 | 0.086 | 41.1 | 25.1 | 16.1 | 17.7 |
| Â | 1 | 0.408 | 9.2 | 21.4 | 13.9 | 55.4 | 0.164 | 15.6 | 15.5 | 46.2 | 22.6 | 0.448 | 15.2 | 11.6 | 63.2 | 10.1 |
A→C | -1 | 0.063 | 23.9 | 37.7 | 23.3 | 15.1 | 0.171 | 35.2 | 26.0 | 33.5 | 5.3 | 0.215 | 16.5 | 50.1 | 15.1 | 18.4 |
| Â | 1 | 0.088 | 33.1 | 12.5 | 34.4 | 20.0 | 0.019 | 30.0 | 21.6 | 30.4 | 18.1 | 0.061 | 27.9 | 19.2 | 37.4 | 15.6 |
A→T | -1 | 0.087 | 18.8 | 37.0 | 30.4 | 13.8 | 0.061 | 16.8 | 29.4 | 35.0 | 18.9 | 0.161 | 17.3 | 45.5 | 15.0 | 22.2 |
| Â | 1 | 0.235 | 10.9 | 39.9 | 13.8 | 35.5 | 0.229 | 7.0 | 27.3 | 25.9 | 39.9 | 0.032 | 20.4 | 21.5 | 33.6 | 24.5 |
C→A | -1 | 0.042 | 22.3 | 33.0 | 29.1 | 15.5 | 0.073 | 38.1 | 24.7 | 25.1 | 12.1 | 0.127 | 13.2 | 41.5 | 22.3 | 23.0 |
| Â | 1 | 0.043 | 21.8 | 27.4 | 34.7 | 16.0 | 0.083 | 20.9 | 39.8 | 17.6 | 21.8 | 0.010 | 30.5 | 27.1 | 22.7 | 19.8 |
C→G | -1 | 0.088 | 17.6 | 36.8 | 17.8 | 27.8 | 0.013 | 31.5 | 21.0 | 27.2 | 20.3 | 0.281 | 11.9 | 48.6 | 11.4 | 28.1 |
| Â | 1 | 0.141 | 25.4 | 33.2 | 9.5 | 31.9 | 0.161 | 16.1 | 37.4 | 13.1 | 33.4 | 0.024 | 23.6 | 28.3 | 20.2 | 27.9 |
G→C | -1 | 0.043 | 26.0 | 20.5 | 36.2 | 17.3 | 0.221 | 40.3 | 11.0 | 38.8 | 9.9 | 0.062 | 22.4 | 25.0 | 18.2 | 34.4 |
| Â | 1 | 0.092 | 39.4 | 18.3 | 15.7 | 26.6 | 0.039 | 21.3 | 32.7 | 19.8 | 26.2 | 0.081 | 21.6 | 22.3 | 40.7 | 15.3 |
G→T | -1 | 0.040 | 19.2 | 29.5 | 32.7 | 18.5 | 0.077 | 20.7 | 31.6 | 34.8 | 12.9 | 0.085 | 17.2 | 28.0 | 19.7 | 35.1 |
| Â | 1 | 0.407 | 7.5 | 55.9 | 12.1 | 24.6 | 0.181 | 11.6 | 43.9 | 29.0 | 15.5 | 0.116 | 14.1 | 37.5 | 32.4 | 16.0 |
T→A | -1 | 0.028 | 24.2 | 33.7 | 21.1 | 21.1 | 0.069 | 32.2 | 34.4 | 18.9 | 14.4 | 0.189 | 18.0 | 44.1 | 11.1 | 26.8 |
| Â | 1 | 0.269 | 8.3 | 46.9 | 16.7 | 28.1 | 0.153 | 10.0 | 23.3 | 40.0 | 26.7 | 0.170 | 19.6 | 19.2 | 48.1 | 13.1 |
T→G | -1 | 0.118 | 15.2 | 34.1 | 17.4 | 33.3 | 0.046 | 20.4 | 19.5 | 35.4 | 24.8 | 0.272 | 11.9 | 48.4 | 11.9 | 27.8 |
| Â | 1 | 0.497 | 3.0 | 51.5 | 12.1 | 33.3 | 0.221 | 9.7 | 19.5 | 47.8 | 23.0 | 0.141 | 16.6 | 18.7 | 45.9 | 18.9 |