Figure 2
From: Causal reasoning identifies mechanisms of sensitivity for a novel AKT kinase inhibitor, GSK690693
Changes in RNA expression levels of genes controlled by FOXO3A support transcriptional activation of FOXO. Upper Panels: Genes that are consistent with increased transcriptional activity FOXO3A are green, those inconsistent are red. Lower panels: Genes that are consistent with increased transcriptional activity FOXO3A are red, those inconsistent are green. Both panels: Genes that are not considered to be changed due to a non-significant fold change or p-value are white. Genes which are inconsistent with the predicted activity are represented in Additional file 1 Table S1 with an "X".