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Table 2 The nested case-control study of T2DM

From: Copy number variation at leptin receptor gene locus associated with metabolic traits and the risk of type 2 diabetes mellitus

Case-control

E2 DNA copy number groups

Odds ratio (OR)

CI (95%)

P value*

 

Low CN (1X)

High CN (2X)

Sum

   

T2DM case subjects (n = 135)

86 (63.7%)

49 (36.3%)

135 (100%)

1.92

1.26~2.96

0.003

non-T2DM control subjects (n = 258)

123 (47.7%)

135 (52.3%)

258 (100%)

   

Total (n = 393)

209 (53.2%)

184 (46.8%)

393 (100%)

   
  1. P value*: Logistic regression analysis