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Figure 4 | BMC Genomics

Figure 4

From: A versatile palindromic amphipathic repeat coding sequence horizontally distributed among diverse bacterial and eucaryotic microbes

Figure 4

Representative genomic inventories and predicted topologies of membrane proteins containing PARCEL domains. Inventories of PARCEL-containing ORFs in the genomes of taxa listed at the left are shown. The total ORFs per genome, and the number representing various categories of membrane protein (A-G) or lacking membrane-targeting sequences (H) are indicated. Cartoons show the locations of PARCEL domain tracts (tandemly arrayed red boxes) relative to the N- and C-termini of the respective ORFs (rods), and to the plasma membrane (bilayers represented by parallel planes). Topologies include: (A) monotopic bacterial LP, anchored by N-terminal lipid modification; (B and C) bitopic TM proteins of different orientations; (D-G) polytopic proteins with two (D-F) or more (G) TM segments. Topology (B) includes proteins with predicted SPs (other than LPs). Topology (G) represents proteins with any number (> 2) of TM domains. Locations of PARCEL domains in ORFs are not to scale and depict only their positions relative to the features shown. The inside or outside of the membrane is not indicated although PARCEL domains were most often predicted to lie outside.

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