Comparative microarray analysis of Rhipicephalus (Boophilus) microplus expression profiles of larvae pre-attachment and feeding adult female stages on Bos indicus and Bos taurus cattle

Table 1 A summary of EST descriptions and the number of transcripts involved in tick attachment and host response modulation by ticks expressed differentially (p ≤ 0.001) in microarray comparisons between larvae vs frustrated larvae.

No. of R. microplus transcripts per category for: Larvae vs frustrated larvae microarray comparison
	Highly expressed in FL (Fold range)		Highly expressed in L (Fold range)
Transcript Category	Brahman cattle	Holstein-Friesian cattle	Brahman cattle	Holstein-Friesian cattle	References
Serpin-1				1 (2.5)	[50–54]
Serpin-2				1 (2.4)	[50–54]
Hemelipoglycoprotein	2 (1.6 - 2.3)	1 (1.7)		1 (1.8)	[48, 61]
Esterases	1 (2)	1 (1.7)		1 (1.6)	[55–58]
Histamine Binding proteins	3 (1.8 - 2.2)				[62, 63]
Lipocalin	2 (2.3 - 2.9)	2 (1.6 -2.2)			[26, 38]
GGY Domain	6 (1.8 - 4.5)	2 (1.7 -2)			[23, 31]
Secreted Salivary	2 (1.6 - 2)	1 (1.7)
Cuticle proteins	4 (1.5 - 2.7)				[64, 82]
Metis (metalloprotease)	1 (3)	1 (3.8)			[44–46]
Microplusin	1 (2.4)	1 (2.8)			[36, 37]
Ixoderin		1 (1.8)			[43]
lospin		1 (2)			[32, 41]
Serine protease		1 (1.8)			[32, 41, 50, 68]
Carboxipeptidase A		1 (1.7)
Cytochrome P450		1 (1.9)
Cytochrome C oxidase	2 (1.5 -2)				[48]
Heat Shock protein	3 (1.7 - 2.5)	6 (1.6 - 3)			[47]
Glutathione S transferase	1 (1.8)				[49]
No Significant Similarities	75 (1.6 - 5)	80 (1.5 - 4.5)
Unnamed	13 (1.7 - 2.7)	14 (1.54 - 3.2)
Total	116	114		4

ISSN: 1471-2164