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Figure 2 | BMC Genomics

Figure 2

From: Regulation of gene expression by FSP27 in white and brown adipose tissue

Figure 2

Comparison of the gene expression profile of FSP27- deficient mouse white adipocytes with that of Pgc1α/Pgc1β double deficient mouse brown adipocytes, the Pparα- deficient mouse WAT or the cells over-expressing PPARγ2. The up-regulated genes (↑) in the white adipocytes of FSP27- null mice were compared with the following: 1) the down-regulated genes (↓) in Pgc1α-/- differentiated brown adipocytes expressing a siRNA specific for Pgc1β (Pgc1α-/- PGC1βsiRNA), 2) the down-regulated genes (↓) in the WAT of Pparα-/- mice (Pparα-/-) or 3) the up-regulated genes (↑) in the PPARγ2 over-expressing NIH-3T3 cells (PPARγ2). The number in the over-lapping area represents the number of genes that have conserved changes between the two cell types in the comparison.

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