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Table 1 The ten most up-regulated and ten most down-regulated genes in the WAT of FSP27-null mice

From: Regulation of gene expression by FSP27 in white and brown adipose tissue

Name

Gene Title

Fold

Ten most upregulated genes

COX8B

cytochrome c oxidase, subunit 8B pseudogene

40.06

ELOVL3

elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3

11.9

NDG2

Nur77 downstream gene 2

8.35

CIDEA

cell death-inducing DFFA-like effector a

8.22

COX7A1

cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)

6.74

CA1

carbonic anhydrase I

6.72

PDK4

pyruvate dehydrogenase kinase, isozyme 4

5.83

CCRN4L

CCR4 carbon catabolite repression 4-like (S. cerevisiae)

5.69

NAP1L5

nucleosome assembly protein 1-like 5

5.63

9530008L14RIK

RIKEN cDNA 9530008L14 gene

5.59

Ten most downregulated genes

PRTN3

proteinase 3 (serine proteinase, neutrophil, Wegener granulomatosis autoantigen)

-26.45

RPGR

retinitis pigmentosa GTPase regulator

-23.68

IGL-V1

immunoglobulin lambda chain, variable 1

-18.31

MEST

mesoderm specific transcript homolog (mouse)

-14.68

EAR11

eosinophil-associated, ribonuclease A family, member 11

-13.50

Tsr2

TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)

-13.15

NAP1L3

nucleosome assembly protein 1-like 3

-12.85

MS4A6D

membrane-spanning 4-domains, subfamily A, member 6D

-11.98

SFRP5

secreted frizzled-related protein 5

-11.88

TOP2A

topoisomerase (DNA) II alpha 170 kDa

-10.89