|
Genes
|
Tg37xNFH-Cre
|
Tg37xNFH-Cre
| |
|---|
| |
Microarray
|
QPCR
|
Protein
|
|---|
| |
(log2 ratio)
|
(ΔΔ CT)
| |
|---|
|
10 weeks
| | | |
|
Glrx3
|
-0.6
|
0.34
|
glutaredoxin 3
|
|
Atp13a1
|
0.81
|
-0.08
|
ATPase type 13A1
|
|
Prnp Tg37
|
ND
|
-5.62
|
Prion protein
|
|
14 weeks
| | | |
|
AV451297.1
|
-2.62
|
-0.02
|
Hypothetical protein
|
|
Ifitm3
|
-1.41
|
-0.12
|
Interferon-induced transmembrane protein 3
|
|
Erf1
|
-1.19
|
-1.12
|
Eukaryote class I release factor
|
|
Bace1
|
-0.48
|
-0.02
|
beta-site APP-cleaving enzyme 1
|
|
BB217622.2
|
0.81
|
0.64
|
Unknown
|
|
Riken D17
|
0.79
|
0.31
|
Unknown
|
|
Fgf2
|
0.48
|
0.47
|
fibroblast growth factor 2
|
|
Prnp Tg37
|
ND
|
-6.43
|
Prion protein
|
- Differentially expressed genes detected by the microarray analysis are listed with the calculated differential ratio (log2) alongside the observed delta-delta CT resulting from the QPCR experiment. The comparative Ct method is known as the 2 - [delta][delta]Ct method, where delta delta Ct = [delta]Ct, sample - [delta]Ct, reference. Age of the analyzed mice is mentioned.
