Figure 2

Relationship of Rhipicephalus sanguineus Kunitz domain proteins to other related tick proteins. The circular phylogram is based on the alignment of sequences derived from this study and homologous sequences obtained from the NR database from NCBI, and from tick sequences derived from dbEST. The red branches have bootstrap support above 75% (10,000 replicates). The bar at the centre indicates 20% amino acid divergence. The R. sanguineus sequences are indicated by a circle, and start with RS-. The sequences obtained from the NR database are indicated by 5 letters (3 from the genus and 2 from the species name) followed by the NCBI accession number. Remaining sequences were deduced from dbEST and are available from Francischetti et al. [8].