Table 6 Selected Genes and their potential regulators in rank order
From: A systems approach to mapping transcriptional networks controlling surfactant homeostasis
Gene TF Rank | ELOVL1 | SLC34A2 | SOAT1 | ZDHHC3 | LPCAT1 | STARD4 | DLK1 | PRDX6 | ABCA3 |
|---|---|---|---|---|---|---|---|---|---|
1 | SREBP (Srebf1/2) | CEBP (Cebpa/b/g) | SREBP1 (Srebf1/2) | SREBP1 (Srebf1) | CEBP (Cebpa/b/g) | SREBP1 (Srebf1) | CEBP (Cebpa/b/g) | CEBP (Cebpa/b/g) | SREBP1 (Srebf1) |
2 | CEBP (Cebpa/b/g) | ETS1 (Ets1) | ZIC2 (Zic2) | GATA (Gata6) | SREBP1 (Srebf1) | CEBP (Cebpa/b/g) | HNF3 (Foxa1/2) | SREBP (Srebf1/2) | HNF3 (Foxa1/2) |
3 | HNF3 (Foxa1/2) | STAT6 (Stat6) | CEBP (Cebpa/b/g) | HNF3 (Foxa1/2) | NFAT (Ilf3, Nfatc3) | ETS1 (Ets1) | KROX (Egr1) | NFKB (Nfkb1) | TTF1 (Nkx2-1) |
4 | TTF1 (Nkx2-1) | SREBP1 (Srebf1/2) | KROX (Egr1) | XFD1 (NP) | ETS1 (Ets1) | FOXP3 (NP) | SREBP1 (Srebf1) | ETS1 (Ets1) | EGR (Egr1) |
5 | TCF4 (Tcf4) | ERR1 (Esrra) | UF1H3B (Foxa1/2) | IRF1 (Irf1) | EGR (Egr1) | HNF3 (Foxa1/2) | HNF1 (Hnf1a/1b) | HNF3 (Foxa1/2) | KROX (Egr1) |
6 | NFKB (Nfkb1) | LMO2COM (Lmo2) | IRF1 (Irf1) | FREAC7 (NP) | STAT6 (Stat6) | ETS2 (Ets2) | TAXCREB (Creb1) | TTF1 (Nkx2-1) | E2F (E2f1-5) |
7 | ZIC2 (Zic2) | HEB (Tcf12) | LXR (Nr1h2) | TTF1 (Nkx2-1) | E2F (E2f1-5) | ATF1 (Atf1) | GATA1 (Gata1) | TCF4 (Tcf4) | CEBP (Cebpa/b/g) |
8 | SMAD4 (Smad4) | HNF3 (Foxa1/2) | LMO2COM (Lmo2) | EGR (Egr1) | GATA1 (Gata1) | HNF4A (Hnf4a) | ETS1 (Ets1) | NRF2 (Gabpa) | GATA (Gata6) |
9 | BARBIE (NP) | TATA (Tbp) | WT1 (Wt1) | ZF5 (Zfp161) | IRF1 (Irf1) | GATA3 (Gata6) | WT1 (Wt1) | SMAD4 (Smad4) | ZNF219 (Zfp219) |
10 | ETS2 (Ets2) | HNF4A (Hnf4a) | SMAD4 (Smad4) | AP2G (Tcfap2c) | AP2G (Tcfap2c) | ERR1 (Esrra) | STAT (Stat3) | GRE (Nr3c1) | WT1 (Wt1) |