Table 5 Selected differentially expressed (DE) genes in the expression profile of 'Susceptible' animals 24 hours post-inoculation
From: Gene expression profiling in the lungs of pigs with different susceptibilities to Glässer's disease
Genes grouped by function | Genbank human RefSeq ID | S v C fold change | S v FR fold change |
|---|---|---|---|
More highly expressed in 'Susceptible' animals | |||
Pro inflammatory cytokine/cytokine receptors | |||
Colony stimulating factor 3 receptor ( CSF3R ) | NM_172313 | +5.99 | +5.68 |
S100 calcium binding protein A9 ( S100A9 ) | NM_002965 | +5.40 | +6.70 |
S100 calcium binding protein A12 ( S100A12 ) | NM_005621 | +3.45 | +3.38 |
Pleiotrophin (PTN) | NM_002825 | +2.97 | +2.75 |
Chemokine (C-X-C motif) ligand 2 ( CXCL2 ) | NM_002089 | +2.79 | +2.84 |
Anti inflammatory cytokine/cytokine receptors | |||
Interleukin 10 ( IL10 ) | NM_000572 | +2.68 | +4.29 |
CD163 antigen ( CD163 ) | NM_203416 | +2.65 | +3.07 |
Neutrophil granule/phagocytosis proteins | |||
Lactotransferrin ( LTF ) | NM_002343 | +16.47 | +9.19 |
Matrix metalloproteinase 9 (MMP9) | NM_004994 | +3.87 | +4.89 |
Transcobalamin I (TCN1) | NM_001062 | +2.55 | +4.64 |
Acyloxyacyl hydrolase ( AOAH ) | NM_001637 | +2.12 | +2.04 |
Lipid mobilization and metabolism | |||
Resistin (RETN) | NM_020415 | +12.77 | +15.04 |
Solute carrier family 2 member 3 (SLC2A3) | NM_006931 | +3.36 | +2.89 |
Alpha-2-glycoprotein 1, zinc binding (AZGP1) | NM_001185 | +2.83 | +3.72 |
Lipoprotein lipase (LPL) | NM_000237 | +2.62 | +5.05 |
Retinol binding protein 4 (RBP4) | NM_006744 | +2.60 | +6.54 |
Less highly expressed in Susceptible animals | |||
Extracellular matrix components | |||
Fibronectin 1 ( FN1 ) | NM_212482 | -1.89 | -2.84 |
Dermatopontin ( DPT ) | NM_001937 | -2.11 | -2.35 |
Transforming growth factor, beta-induced, (TGFBI) | NM_000358 | -2.13 | -4.68 |
Microfibrillar associated protein 5 ( MFAP5 ) | NM_003480 | -2.14 | -2.43 |
Elastin ( ELN ) | NM_000501 | -4.54 | -3.82 |
Extracellular matrix growth factors | |||
Transforming growth factor beta 2 (TGFB2) | NM_003238 | -2.35 | -3.58 |
P311 protein (P311) | NM_004772 | -4.14 | -4.5 |