MptpB and related phosphatases have both protein phosphatase and lipid phosphatase activity. (A) Specific activity (SA) for His-MptpB WT, Lmo1800 WT, Lmo1935 WT, His-LM1 and His-TbPTP1  towards phosphorylated peptide substrates tested. (B) Specific activity of the same proteins towards PI substrates is shown. None of the phosphatases had activity on PI(3,4)P2, PI(4,5)P2 or PI(3,4,5)P3. Error bars indicate SEM.