Positional differences in the wound transcriptome of skin and oral mucosa

BMC Genomics

Table 4 Early up-regulated genes: enriched groups of functionally related genes

	Skin		Tongue
Terms	Members (#)	Score	Members (#)	Score
Interferon α, β and δ/cytokine	16 (Group 1)	9.77
Chemokine	12 (Group 2)	9.58	10 (Group 1)	6.46
Cell differentiation/apoptosis	8 (Group 3)	3.85	1
Positive regulation of protein kinase activity	4 (Group 4)	3.68
Regulation of metabolic/biological process	4 (Group 5)	2.91
Pattern recognition receptors (TLR related)	7 (Group 6)	2.82
Ribosome/organelle organization	8 (Group 7)	2.5
Matrix metallopeptidase (MMP)	6 (Group 8)	2.04
Negative regulation of cell proliferation			4 (Group 2)	3.34
GTP binding			14 (Group 3)	3.08
Keratinization/epidermal development			4 (Group 4)	2.27

Table contains a list of top enriched groups of annotation terms and enrichment scores derived from DAVID gene functional classification analysis.
Term: consensus annotation terms shared by a group of genes.
Member (#): numbers of differentially expressed transcripts associated with the term.
Score: statistical significance of the enrichment based on overall EASE scores.

ISSN: 1471-2164