Pair-wise comparisons of the distance to the origin of replication (Ori) for orthologous genes between A. actinomycetemcomitans strains. The distances for genes on the leading strands were calculated directly from the position of Ori. The distances for genes on the lagging strands were calculated as (genome length-the distance to Ori). The linear trend line by Pearson's correlation is provided. The low r2 values indicate a lack of correlation in the gene positions between D7S-1 and HK1651. (a) Comparison between HK1651 and D11S-1. There is an apparent correlation in the locations of orthologous genes in the strains. (b) Comparison between D7S-1 and HK1651. Although there is a hint of an overall linear relationship, the distribution pattern suggested that the locations of the orthologous genes were poorly correlated. (c-e) Comparisons between D7S-1 and HK1651 with genes of different categories. Again, little correlations were found in the locations of the orthologous genes between these strains.