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Table 3 Unique mapping of reads to AS-WTSI reference sequence.

From: Experimental evolution, genetic analysis and genome re-sequencing reveal the mutation conferring artemisinin resistance in an isogenic lineage of malaria parasites

  number of
bases
mapped
  % of genome sequence (WTSI) mapped
  in silico (unique) experimental (unique)
    AS AS-30CQ
    > = 5 > = 10 > = 5 > = 10
36 mer 18,574,867 98.63 97.78 95.88   
41 mer 18,606,976 98.80    97.95 96.96
  1. In silico analysis shows the number of bases and percentage of genome which can be uniquely mapped by sequence reads (equivalent to theoretical maximum). Experimental analysis shows the percentage of genome actually mapped by such reads, at different read-coverages (> = 5, > = 10) in AS-sens or AS-30CQ. AS-sens and AS-30CQ were analysed with 36 - and 41 base reads, respectively.