Table 2 Genes up-regulated ≥3-fold by BF/S+L/Ep or cyotpiloyne at 4 hours.
From: Differential functional genomic effects of anti-inflammatory phytocompounds on immune signaling
| Gene Expresion Ratio (Test + LPS): LPS only | ||||||
|---|---|---|---|---|---|---|
| Gene Symbol | Gene ID | shikonin | emodin | cytopiloyne | BF/S+L/Ep | |
| Cytokines | CSF1 | 1435 | 0.91 | 1.69 | 3.54 | 3.12 |
| IL5 | 3567 | 0.87 | 1.35 | 2.77 | 3.01 | |
| TNFSF14 | 8740 | 1.01 | 1.36 | 2.67 | 3.03 | |
| Chemotaxis & Cell Migration | CCR1 | 1230 | 0.87 | 1.3 | 2.91 | 3.09 |
| CCR8 | 1237 | 0.78 | 1.48 | 2.76 | 3.14 | |
| ITGAX | 3687 | 1.08 | 1.38 | 2.88 | 3.19 | |
| CXCR4 | 7852 | 1.21 | 1.63 | 3.33 | 2.63 | |
| MADCAM1 | 8174 | 0.82 | 1.45 | 3.04 | 3.39 | |
| Inflammatory Responses | CD14 | 929 | 0.9 | 1.56 | 3.24 | 3.26 |
| MAP2K4 | 6416 | 1.25 | 1.4 | 2.59 | 3.56 | |
| TLR3 | 7098 | 0.91 | 1.33 | 2.35 | 3.06 | |
| IL1R2 | 7850 | 0.91 | 1.49 | 2.64 | 3.13 | |
| TNFRSF10D | 8793 | 0.84 | 1.4 | 2.86 | 3.28 | |
| TBX21 | 30009 | 0.66 | 1.34 | 2.89 | 3.2 | |
| Other | SHC1 | 6464 | 0.89 | 1.22 | 2.4 | 3.2 |
| ADAMDEC1 | 27299 | 1.14 | 1.79 | 2.71 | 3 | |
