Table 1 List of 106 transcription factor families (from UCSC genome web browser, Conserved TFBS track) and their detailed methylation profiles in hearts and sperm.
From: Genome-wide conserved consensus transcription factor binding motifs are hyper-methylated
| Â | Â | SPERM | |
|---|---|---|---|
| Â | Â | Hyper-methylated | Hypo-methylated |
HEART | Hyper-methylated | AHR-ARNT, AML1, AP, AREB6, ARP1, ATF, BACH, BRACH, CDP, CEBP, CHOP, COMP1, COUP, CP2, CREB, EN1, ER, FAC1, GATA, GCNF, GFI1, GR, HEN1, HMX1, HOX, HSF, HTF, IK, ISRE, LMO2COM, LUN1, LYF1, MEIS1, MIF1, MRF2, MSX1, MYB, MYCMAX, MYOD, MYOGNF1, MZF1, NCX, NF1, NFE2, NFKB, NRSF, OLF1, EP300, P53, PAX, PBX1, PPAR, RFX1, ROAZ, RORA, RP58, RREB1, SEF1, SPZ1, SREBP, SRF, STAT, TAL1-E47, TCF, TGIF, USF, XBP1, YY1, ZIC, ZID | - |
| Â | Hypo-methylated | CETS1P54, E2F, E4BP4, EGR, ELK1, MAZR, NFY, NRF1, SRY | CHX10, FOX, FREAC, LHX3, MEF2, POU, RSRFC4, S8, HFH, SOX, SP1, TATA, TBP |
| Â | Neutral | BRN2, CREL, HLF, IRF, NFAT, NGFIC, NMYC, TST1 CDC5, OCT | CART1, NKX, EVI1, HNF |